Biotechnology & nanotechnology
fereshteh jookar kashi; Zohreh Boroumand
Volume 28, Issue 1 , January and February 2021, , Pages 144-155
Abstract
Introduction: The bacteria with a remarkable ability to regenerate heavy metal ions are considered biological factories or important nano-factories to produce nanoparticles. The bacterial production of nanoparticles as a green and one-step method can overcome production problems and disadvantages through ...
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Introduction: The bacteria with a remarkable ability to regenerate heavy metal ions are considered biological factories or important nano-factories to produce nanoparticles. The bacterial production of nanoparticles as a green and one-step method can overcome production problems and disadvantages through physical and chemical methods. Materials and Methods: In this study, bacteria isolates were taken from soil samples of Nakhlak mine. One silver resistant bacterial strain was selected for the production of silver nanoparticles. This strain synthesized silver nanoparticles with supernatant and biomass. The nanoparticles synthesized were characterized using XRD and SEM. The antimicrobial activity of the nanoparticles was determined. Results: The silver resistance bacteria were isolated from soil samples. One silver resistant bacterial strain was selected for the production of silver nanoparticles. The nanoparticles showed good antimicrobial activity against standard strains of tested microorganisms. Conclusion: The nanoparticle synthesized by bacterial strain isolated from Nakhlak mine is a promising new biological source for synthesizing silver nanoparticles with potent antimicrobial activity. According to the results, this compound can be used to make disinfectants
Microbiology
Morteza Yazdani; Fereshteh Jookar Kashi; Akram Rahimi-Moghaddam
Volume 26, Issue 5 , November and December 2019, , Pages 555-565
Abstract
Background: Considering the adverse effects of synthetic antioxidants, anticancer drugs and antibiotics on human health, in this study, bioactivities of Mentha longifolia essential oils collected from Marivan and Qaza An were examined and compared with each other for identification a natural alternative ...
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Background: Considering the adverse effects of synthetic antioxidants, anticancer drugs and antibiotics on human health, in this study, bioactivities of Mentha longifolia essential oils collected from Marivan and Qaza An were examined and compared with each other for identification a natural alternative of synthetic antioxidants, anticancer drugs and antibiotics.Materials and Methods: Essential oil of M. longifolia leaves and stems collected from Marivan and Qaza An was prepared using solvent-free microwave extraction method. The essential oil components were identified by gas chromatography/mass spectrometry. The antioxidant and cytotoxicity activity of the essential oils were determined via β–carotene bleaching assay and brine shrimp lethality test, respectively. The antimicrobial activity of the essential oils was evaluated by the agar well diffusion method and by determination of minimum inhibitory concentration.Results: The main components of M. longifolia essential oil collected from Marivan were pulegone (81.45%) and isopulegol (8.39%) and the main components of M. longifolia essential oil collected from Qaza An were pulegone (48.29%) and piperitenone oxide (23.53%). The inhibition of linoleic acid oxidation by M. longifolia essential oils collected from Marivan, Qaza An and BHT were 80.02%, 78.59% and 95.50%, respectively. The LC50 of the M. longifolia essential oils collected from Marivan, Qaza An and vincristine sulfate were 53.47μg/ml, 55.96 μg/ml and 0.751 μg/ml, respectively. M. longifolia essential oils had good antimicrobial activity, especially against gram-positive bacteria.Conclusion: M. longifolia essential oils have significant antioxidant, antimicrobial and anticancer activity and can be introduced as alternatives of synthetic antioxidants, antibiotics and anti-cancer drugs.